FilterTec Normal Flow Filtration Direct Flow Filtration System SetupThe FilterTec is a software-driven laboratory scale Normal Flow Filtration (NFF) system that automatically monitors, adjusts and documents pre-filter back pressure and permeate flow rate to optimize filtration speed, maximize filter throughput, and scientifically evaluate or compare different filters using calculations such as Vmax and total filter throughput. The automatic documentation and alarm/pump stop settings allow the user to focus on other tasks while the system is running.

The user-selectable alarms allow automatic stopping once a given filter back pressure or minimum filtrate flow rate is reached. When sold with SciDoc, documentation capabilities include 15 real-time filtration parameters such as: permeate flow rate, quantity, pressure, Vmax, etc… over time. The patented R/P stat mode has been proven to increase filter throughput up to 35% saving significant money on filters over time.

FilterTec Advantage

  • Patented filtration method provides significant cost savings. This automated method results in a 30-50% increase in filter capacity utilization.
  • Dedicated application tools for filterability testing and Vmax determination with automated data collection of up 15 filtration parameters.
  • No need for manual data collection.
  • The FilterTec is easy to use and has a small (6" x11") footprint.

FilterTec Applications: Versatile Precision

On-board application software automates and documents a range of liquid handling tasks:
Constant Rate
Constant Pressure

Automated Normal Flow Filtration (NFF)

Laboratory Filtration, up to 4.0 liters/min

  • Documented Filtration Parameters
    • Time: HH:MM:SS
    • Elapsed Time
    • Filtrate Weight (FQ)
    • Nominal Pump Rate (FF)
    • Filtrate Rate, Scale, (FP)
    • Constant Rate Quantity (CPQ)
    • Constant Pressure Quantity (CPQ)
    • Inlet Pressure, Filter #1 (P1)
    • Inlet Pressure, Filter #2 (P2)
    • Inlet pressure, Filter #3 (P3)
    • Time / Weight Ratio (T/W)
    • Maximum Filtrate Volume, Vmax
    • Filter Flux (LMH)
    • Pump Direction (CW/CCW)
    • Alarms:
      • HP= Hi Pressure
      • LF= Lo Flow
      • FW= Filtrate Weight
    FilterTec NFF System provides significant cost savings when used with any commercially available membrane or depth filters.
  • The FilterTec utilizes a peristaltic pump head as well as a disposable pressure sensor (see SciLog's disposable sensors).
  • A user-selected pump rate (or time-based rate ramp) is implemented until a user-defined pressure level is reached, e.g. 20 psi.
  • At this point, the filter is substantially plugged-up, the FilterTec switches from a rate control to a pressure controlled fluid delivery.
  • The FilterTec automatically maintained the selected pressure limit by modulating, i.e. decreasing, the pump output.
  • When the pump output reaches a user-selected lower pump rate limit, e.g. 1 ml/min, the FilterTec safely stops the filtration process.
  • The filtration progress is graphically shown above (chart 1). In this example, a Sartobran 300 was used to filter a diluted protein solution. Under the flow rate and pressure conditions shown, a filtrate volume of 1491 ml was collected during the constant pump rate interval. An additional 715 ml of filtrate was collected during the constant pressure (20psi) interval.

Automated Filter Capacity Determination, Vmax

FilterTec Normal Flow Filtration Direct Flow Filtration System SetupGenerates/documents Filtration Scale-up Data

  • For Vmax determinations the FilterTec utilizes a pressure sensor and an electronic scale. The FilterTec rapidly ramps up the pump rate and maintains a user-selected pressure.
  • The FilterTec collects and documents the filtrate weight. The parameter "Time/Filtrate Weight" is plotted against "Time". The inverse of the resulting slope represents Vmax.
  • Up to 15 filtration parameters are monitored and documented during filtrate collection. (listed above)

FilterTec Product Information

FilterTec Options
  • Pump Head, Motor Options & Flow Rate:
    1. Tandem 1081 peristaltic pump head with 8 RPM motor. Flow rate*: 0.03 to 24 ml/min.
    2. Tandem 1081 peristaltic pump head with 160 RPM motor. Flow rate*: 0.5 to 554 ml/min.
    3. Tandem 1082 peristaltic pump head with 600 RPM motor. Flow rate*: 59 to 2,258 ml/min.
    4. Tandem 1081 peristaltic pump head with 600 RPM motor. Flow rate*: 2 to 1,515ml/min.
  • Pressure Range: Maximum pressure output at tandem peristaltic pump head is 45 psi.
  • Pressure Displayed: Pressure displayed with a resolution of 0.1 psi; choice of bar, psi, kpa
  • Pressure Sensors: Accommodates up to three (3) disposable pressure sensors. The calibrated pressure range is 0-60 psi. Can be re-calibrated using an external pressure reference source.
  • FilterTec Balance Options:
    1. Balance with capacity of 2,000 grams x 0.01 g resolution included with FilterTec CP-8.
    2. Balance with capacity of 8100 grams x 0.1 g resolution included with all other FilterTecâ„¢ models.
    3. Larger Balance Models Available
      Other Balance Options Available
FilterTec Model Part Numbers

Additional Models May Be Available. Contact SciLog For More Information

Per Channel mL/min
Part Number VAC Model Motor Pump Head Type Flow Rates Max
RPM Min. Max. PSI
200-FLTR-7181 110V CP-120 160 Tandem Peristaltic (1081) 0.5 554 45-50 psi
201-FLTR-7181 220V
Description:

FILTERTEC CP-120 mounted with TANDEM 1081 peristaltic head, uses Masterflex thin-walled tubing: 13,14,16,17,25. Max. 160 RPM motor, Flow Range: 0.5 to 554 ml/min, depending upon tubing size.
System Includes:

  • 8100 gram x 0.1 gram balance,
  • Pump & Controller
  • Fittings kit with initial tubing,
  • 3 disposable pressure sensors (SciPres Luer),
  • Interfacing cable to balance.
  • Rod & Clamp to hold filters
Tested as a system. Ready to use. Tandem max. 45 to 50 psi.
200-FLTR-7681 110V CP-200 600 Tandem Peristaltic (1081) 2 1515 45-50 psi
201-FLTR-7681 220V
Description:

FILTERTEC CP-200 mounted with TANDEM 1081 (uses Masterflex thin-walled tubing sizes: 13,14,16,17,25) peristaltic head, Max. 600 RPM motor, Flow Range: 2 to 1515 ml/min, depending upon tubing size.
System Includes:

  • 8100 gram x 0.1 gram balance,
  • Pump & Controller
  • Fittings kit with initial tubing,
  • 3 disposable pressure sensors (SciPres Luer),
  • Interfacing cable to balance.
  • Rod & Clamp to hold filters
Tested as a system. Ready to use. Tandem max. 45 to 50 psi.
200-FLTR-7682 110V CP-200 600 Tandem Peristaltic (1082) 59 2258 45 psi
201-FLTR-7682 220V
Description:

FILTERTEC CP-200 mounted with TANDEM 1082 peristaltic head, uses Masterflex thick-walled tubing sizes: 15,24,35 Max. 600 RPM motor, Flow Range: 59 to 2258 ml/min, depending upon tubing size.
System Includes:

  • 8100 gram x 0.1 gram balance,
  • Pump & Controller
  • Fittings kit with initial tubing,
  • 3 disposable pressure sensors (SciPres Luer),
  • Interfacing cable to balance.
  • Rod & Clamp to hold filters
Tested as a system. Ready to use. Tandem max. 45 to 50 psi.

* Measured in mL/min.

FilterTec Software
  • FilterTec Software: Main menu with five operational modes including:
    1. Constant Rate Mode: Constant Rate/Constant Pressure Filtration with six user-definable alarms.
    2. Constant Pressure Mode: Constant Pressure Filtration with six user-definable alarms.
    3. Programmable R-P Mode: Automated continuous changing of pump rate or pressure with time.
  • Documentation Software for PC:
    1. SciDoc interface software with custom macros for Excel for data compilation.
    2. Complete process analysis with graphing of data.
    3. Real-time verification and documentation of process parameters.
FilterTec System Specs
  • Dimensions: Width: 5.75 in (14.6cm); Height: 8.5 in (212.6); Depth: 11in (27.9).
  • Weight: 14 lbs (6.4kg)
  • Enclosure: 16 Ga, aluminum baked epoxy blue
  • Pressure Range: Maximum pressure output at tandem peristaltic pump head is 45 psi. Has single point recalibration feature.
  • Pressure Displayed: Pressure displayed with a resolution of 0.1 psi; choice of bar, psi, kpa
  • I/O Ports:
    1. First serial port labeled Balance, Male DB9 connector for hook-up of electronic scale.
    2. Second Serial Port labeled "Printer", Female DB9; also used to interface to PC for data storage in an Excel file in your PC.
    3. External I/O port, Female DB37 connector; Used for remote On/Off control of FilterTec via footswitch.
    4. Optional pressure sensor interface available
  • Data Entry: Membrane keyboard with auditory feedback.
  • Power: 115/220-240 VAC, 60/50Hz, 75 Watts; double fused: T1AL 250V (CE: IR35A 250VAC)
  • Use Range: 4 to 40 C, 100% Humidity