PureTec Tangential Flow Filtration Cross Flow Filtration System  ViewPureTec Advantage

Transmembrane
Pressure Vs.
Permeate Flux

Protein
Concentration
vs. Permeate Flux

PureTec system is a software-driven lab scale TFF protein purification system that automatically monitors and adjusts trans-membrane pressure (TMP) or cross flow rate to optimize product yield. User-selectable alarms allow automatic stopping at a given concentration factor or diafiltration exchanges. When sold with SciDoc, documentation capabilities include 17 real time filtration parameters such as TMP, permeate flow rate and quantity, Normalized Water Permeability (NWP), concentration factor, and other parameters over time. The automatic documentation and alarm system allows the user to focus on other tasks while the system is running.

Walk-Away TFF Automation

The PureTec includes operational safety alarms and automated shutdown when filtration benchmarks have been achieved. PureTec maintains user-selected trans-membrane pressure during TFF / Cross-Flow Filtration / Protein Purification operations.

PureTec Tangential Flow Filtration System automates concentration & diafiltration of biopharmceutical solutions. A 500 ml retentate vessel (polysulfone) with magnetic stirrer is included; 50 ml and 1000 ml retentate vessels are available options. Programmable peristaltic system generates a flow rate up 4.0 liters/minute with high precision.

PureTec TFF System also includes three (3) disposable pressure sensors for monitoring feed, retentate and permeate line pressure.

PureTec TFF System includes an electronic scale for monitoring permeate collection rate. Optional printer documents up to 11 filtration parameter including date/time stamp.

PureTec + SciDoc = Automated Documentation

Documented Filtration Parameters
  • Time: HH:MM:SS
  • Permeate Weight
  • Feed Line Pressure
  • Retentate Line Pressure
  • Permeate Line Pressure
  • Trans-Membrane Pressure
  • Feed Flow Rate
  • Permeate Flow Rate
  • Retentate Flow Rate
  • Permeate Flux
  • Concentration Factor
  • Operation Status: RUN, STOP
  • Operational Alarms
  • Monitor 1 Output
  • Monitor 2 Output

The SciDoc Documentation Package, used in conjunction with the PureTec, displays, calculates compiles, and documents 15 filtration parameters; providing you with an instantaneous overview of your filtration progress and status. This Excel based application also automatically populates graphs in real time. The PureTec gives you the information & control you need to optimize your filtration for maximized yield.

PureTec Compatible Filter Cartridges

The PureTec can be used with a variety of TFF Membrane and Hollow Fiber filter sytems, from several manufactures, i.e. Pall, Sartorius, Millipore, etc. If your flow rates will exceed 2000 ml/min, the SciFlex and SciPure systems are capable of these higher flow rates.

PureTec Product Information

PureTec Model Part Numbers

Additional Models Are Available. Contact SciLog For More Information

mL/min
Part Number VAC Model Motor Pump Head Type Flow Rates Max
RPM Min. Max. PSI
200–PURE–7181 110V PureTec CP-120 160 Tandem Peristaltic (1081) 0.5 554 45-50
201-PURE-7181 220V
Description:

PURETEC CP-120 mounted with TANDEM 1081 peristaltic head, uses Masterflex thin-walled tubing: 13,14,16,17,25. Max. 160 RPM motor, Flow Range: 0.5 to 554 ml/min, depending upon tubing size. Customer choice of Luer or Barb Fittings.
System Includes:

  • 8100 gram x 0.1 gram balance,
  • Pump & Controller
  • 500 ml autoclavable polysulfone vessel (no threaded parts, all channels are 316SS with Luer fittings),
  • Powerful variable speed stirrer,
  • Fittings kit with initial tubing,
  • 3 disposable pressure sensors (SciPres Luer),
  • Interfacing cable to balance.
Tested as a system. Ready to use. Tandem max. 45 to 50 psi. Customer choice of Luer or Barb.
200-PURE-7681 110V PureTec CP-200 600 Tandem Peristaltic (1081) 2 1515 45-50
201-PURE-7681 220V
Description:

PURETEC CP-200 mounted with TANDEM 1081 (uses Masterflex thin-walled tubing sizes: 13,14,16,17,25) peristaltic head, Max. 600 RPM motor, Flow Range: 2 to 1515 ml/min, depending upon tubing size.
System Includes:

  • 8100 gram x 0.1 gram balance,
  • Pump & Controller
  • 500 ml autoclavable polysulfone vessel (no threaded parts, all channels are 316SS with Luer fittings),
  • Powerful variable speed stirrer,
  • Fittings kit with initial tubing,
  • 3 disposable pressure sensors (SciPres Luer),
  • Interfacing cable to balance.
Tested as a system. Ready to use. Tandem max. 45 to 50 psi. Customer choice of Luer or Barb.
200-PURE-7682 110V PureTec CP-200 600 Tandem Peristaltic (1082) 59 2258 45
201-PURE-7682 220V
Description:

PURETEC CP-200 mounted with TANDEM 1082 peristaltic head, uses Masterflex thick-walled tubing sizes: 15,24,35 Max. 600 RPM motor, Flow Range: 59 to 2258 ml/min, depending upon tubing size.
System Includes:

  • 8100 gram x 0.1 gram balance,
  • Pump & Controller
  • 500 ml autoclavable polysulfone vessel (no threaded parts, all channels are 316SS with Luer fittings),
  • Powerful variable speed stirrer,
  • Fittings kit with initial tubing,
  • 3 disposable pressure sensors (SciPres Luer),
  • Interfacing cable to balance.
Tested as a system. Ready to use. Tandem max. 45 to 50 psi. Customer choice of Luer or Barb.

* Measured in mL/min.

PureTec Options
  • Pressure Sensors: Accommodates up to three (3) disposable pressure sensors. The calibrated pressure range is 0-60 psi. Any point within this range can be re-calibrated using an external pressure reference source.
  • PureTec Balance Options:
    1. Balance with capacity of 3,000 grams x 0.01 g resolution included with PureTec CP-8.
    2. Balance with capacity of 8,100 grams x 0.1 g resolution included with all other PureTec models.'
    3. Additional Balance Options Are Available
  • PureTec Vessel Options:
    1. 50 mL Polysulfone (autoclavable),
    2. 500 mL Polysulfone (autoclavable),
    3. 1000 mL Polysulfone (autoclavable)
PureTec Software
  • PureTec Software: Main menu with five operational modes including:
    1. Rate Mode: Constant Rate Filtration with five user-definable alarms.
    2. Pressure Mode: Constant Pressure Filtration with five user-definable alarms.
  • Choice of Inlet Pressure or Trans-Membrane Pressure for Control and Alarm.
  • Documentation Software for PC:
    1. SciDoc documentation software with custom macros for Excel data compilation. Sent to you ready to use.
    2. Complete process analysis with graphing of data.
    3. Real-time verification and documentation of process parameters.
PureTec System Specs
  • Dimensions: Width: 5.75 in (14.6cm); Height: 8.5 in (212.6); Depth: 11in (27.9).
  • Weight: 14 lbs (6.4kg)
  • Enclosure: 16 Ga, aluminum baked epoxy blue
  • Pressure Range: Maximum pressure output at tandem peristaltic pump head is 45 psi. Has single point recalibration feature.
  • Pressure Displayed: Pressure displayed with a resolution of 0.1 psi; choice of bar, psi, kpa
  • I/O Ports:
    1. First serial port labeled Balance, Male DB9 connector for hook-up of electronic scale.
    2. Second Serial Port labeled "Printer", Female DB9; also used to interface to PC for data storage in an Excel file in your PC.
    3. External I/O port, Female DB37 connector; Used for remote On/Off control of PureTec via footswitch.
    4. Optional pressure sensor interface available
  • Data Entry: Membrane keyboard with auditory feedback.
  • Power: 115/220-240 VAC, 60/50Hz, 75 Watts; double fused: T1AL 250V (CE: IR35A 250VAC)
  • Use Range: 4 to 40 C, 100% Humidity